In vitro Antiplasmodial Activity and Cytotoxicity of Ten Plants Used as Traditional Medicine in Malaysia

In vitro Antiplasmodial Activity and Cytotoxicity of Ten Plants Used as Traditional Medicine in Malaysia

Dichloromethane and methanolic extracts of each plant were tested for their antiplasmodial activity on chloroquine- resistant strain of Plasmodium falciparum (FCB strain), based on lactate dehydrogenase activity. Cytotoxicity was assessed with the MTT test on MRC-5 human diploid embryonic lung cells. Most extracts of ten selected plants used in Malay traditional medicine in Malaysia had activity in vitro. This supports continued investigations of traditional medicine in the search for new antimalarial agent.

WAN OMAR ABDULLAH, NGAH ZASMY UNYAH, RUKMAN AWANG HAMAT, BAHARUDIN OMAR, MOHAMED KAMEL ABD GHANI, MOHAMMAD RAYANI & GHOLAM REZA HATAM

2011

200827068

Jurnal Sains Kesihatan Malaysia